ผศ.ดร. วันล่า  กุลวิชิต
       (Professor Assistant Wanla Kulwichit, M.D.)

  •  ตำแหน่ง
    • ผู้ศาสตราจารย์
  • ที่อยู่ 4/1 Taksin 35 Bangkok 10600 Thailand  home

    Phone: 66-2-877-8650 work

    Phone: 66-2-256-4578 ext 105

    Email: wkulwich@gmail.com
 

          Education & Training:

1981   - Suankularb High School

1987   - Doctor of Medicine (Honors)Chulalongkorn University, Bangkok, Thailand

1987   - Zertifikat der Mittelstufenprüfung, Goethe Institut, Bangkok (eligibility to enter German Universities without additional

            German Language course requirement)

1991   - Dip. Thai Board of Internal Medicine

1991   - Certificate, Educational Commission for Foreign Medical Graduates (ECFMG), USA

            (eligibility to practice medicine in the United States)

2000   - Certificate in Infectious Diseases Training, University of North Carolina, USA

2004   - Thai Board of Infectious Diseases (Adults)           

 

Professional Experience:

1987-1991    Resident, Internal Medicine, Prince of Songkhla University, Haadyai, Songkhla

1991-1992    Clinical Fellow, Infectious Diseases,  Dept. of Medicine, Chulalongkorn University Hospital, Bangkok

1992-1997    Clinical&Research Fellow, Division of Infectious Diseases, Department of Medicine, and Lineberger Comprehensive Cancer Center,

                   School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA

1998-2000    Research Associate, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill    

2000-2003    Instructor in Medicine and Infectious Diseases, Department of Medicine, Faculty of Medicine Chulalongkorn University 

2003-present Assistant Professor of Medicine, Department of Medicine, Faculty of Medicine Chulalongkorn University 

 

Research Experience:  

 

993-2000    Conducting research on Epstein-Barr virus oncoprotein latent membrane protein 1 and its link to lymphoid malignancies using

                  transgenic mouse models and clinical specimens                                                                 

2000-present  Conducting research on dengue and enteroviral nfections (diagnostic tests and pathogenesis)

2005-present   Conducting research on antimicrobial-resistant bacteria including lactic acid bacteria and nontyphoidal Salmonella

Awards&Honors:                  

1980    First runner-up, Nationwide English Language Test for  Senior High School students, MAC Academic Center

1980    His Majesty The King’s Award for the Best High  School Graduate in Science in Bangkok 

           (written exam competition organized by the Ministry of Education)

1982    Award for the highest scorer in Neuroscience                                                  

1991    Annual Award for the best resident in Internal Medicine, Faculty of Medicine, Prince of Songkhla University

2002-2004 King Ananda Mahidol Foundation’s Research Scholar in Science or Medicine

2003-2005 and 2006-2009  The Thailand Research Fund’s Research Scholar - Dengue Virus Diagnostics and Pathogenesis

2006-   Listed in Marquis Who’s Who in Medicine and Healthcare 6th Edition 2006

2007-   Listed in Marquis Who’s Who in Asia 1st Edition 2007

2007-   Listed in Marquis Who’s Who in The World 24th Edition 2007

2007-   Listed in Marquis Who’s Who in The World 25th Edition 2008 (In Press)

2007-   Listed in Marquis Who’s Who in Science and Engineering 10th Edition 2008 (In Press)

2007   An International Health Professional of The Year by The International Biographical Centre, Cambridge, England      

          http://www.internationalbiographicalcentre.com/

2007 The 2,000 Outstanding Intellectuals of The 21st Century Outstanding Educators Worldwide – 2007

        The Dictionary of International Biography (34th edition)

        The Cambridge Blue Book of Foremost International      Health Specialists

        The International Biographical Centre, Cambridge, England (In Press)

        http://www.internationalbiographicalcentre.com/

 

Societies:                      

1987-present Member, Thai Medical Council

1991-present Member, Infectious Disease Association of Thailand

1994-1997    Member, American Medical Association

1996-1997    Member, International Association for Research on Epstein-Barr Virus and Associated Diseases

2002-present Member, Medical Association of Thailand

2004            Scientific Committee, The 9th Western Pacific Congress on Chemotherapy and Infectious Diseases – December 1-5, 2004

2004-present Member, Royal College of Physicians of Thailand

2006-present Member & Secretary, Subcommittee on Research Affairs, The Royal College of Physicians of Thailand

2004-present Deputy Editor, The Journal of Infectious Diseases and Antimicrobial Agents

2006-           Sentinel Reader in Infectious Diseases, McMaster Online Rating of Evidence (MORE), McMaster University, Canada

 

Journal Peer Reviews  

2006          Clinical Infectious Diseases (listed only non-Thai journals)    

2007          Diagnostic Microbiology and Infectious Diseases

Abstracts:  

1.   Raab-Traub N, Kulwichit W, Edwards RH. Expression of Epstein-Barr Virus Latent Membrane Protein 1 in Transgenic Mice. J Cell Biochem 1994; 18(C): 233. 

2.   Raab-Traub N, Kulwichit W, Edwards RH, Miller W, Paine E, Flynn K, Sadler R, Pathmanathan R. Expression of Epstein-Barr Virus Latent Membrane Protein 1 in Epithelial Cells and in Transgenic Mice. The VI International Conference on Epstein-Barr Virus And Associated Diseases. Cold Spring Harbor Laboratory, Long Island, NY, USA. September 7-11, 1994.  

3.   Kulwichit W, Edwards RH, Davenport EM, Raab-Traub N. Lymphoid Hyperplasia and Malignancies in LMP1 Transgenic Mice. The VII International Conference on Epstein-Barr Virus And Associated Diseases. Hong Kong, November 13-16, 1996. 

4.   Kulwichit W, Edwards RH, Davenport EM, Raab-Traub N. LMP1 Transgenic Mice Develop Lymphoma, with Increased Expression of Several Oncogenes. The XXII International Herpes Virus Workshop. San Diego, CA, USA. August 2-8, 1997. 

5.   Kulwichit W, Edwards RH, Bendt KM, Raab-Traub N. LMP1 Transgenic Mouse Lymphomas: Activation of NF-κB and JNK Signaling Pathways Without Mutations in p53. The XXV International Herpes Virus Workshop. Portland, OR, USA. July 29-August 4, 2000. 

6.   Kulwichit W*, Mekmullica J, Yapom R, Intaraprasong P, Mutirangura A, Nisalak A, Pancharoen C, Thisyakorn U. Diagnosis of dengue infection by reverse transcription-nested polymerase chain reaction in urine specimens. The 1st Asian Congress of Pediatric Infectious Diseases. Pattaya, Thailand. November 10-13, 2002.

* = principal investigator 

7.   Kulwichit W*, Mekmullica J, Krajiw S, Prommalikit O, Yapom R, Intaraprasong P, Arunyingmongkol, Suandork P, Sittichai R, Sakdikul S, Mutirangura A, Pancharoen C, Thisyakorn U, and Nisalak A. Highly-sensitive Virologic Diagnosis of Dengue Infection by A Newly-Developed Protocol of Reverse Transcription-Nested Polymerase Chain Reaction (RT-nested PCR) of Serum/Plasma, Peripheral Blood Leukocyte (PBL), and Urine Specimens. The 41st Annual Meeting of the Infectious Diseases Society of America. San Diego, CA, USA. October 9-12, 2003.

* = principal investigator 

8.      Jaimchariyatam N, Chatsuwan T, Nilgate S, Chongthaleong A, Chindamporn A, Kulwichit W.* Mixed Bacterial Meningitis due to a Co-infection with Enterococcus faecalis and Neisseria meningitides in an HIV-infected Patient. 29th Annual Meeting of The Infectious Diseases Association of Thailand. Hua-Hin, Prachuabkirikhan, Thailand October 4-7, 2003.

* = principal investigator 

9.      Srisawat N, Tanyaowalak W, Bhattarakosol P, Hemachudha T, Kulwichit W.* Detection of Herpes simplex DNA in Cerebrospinal Fluid of a Patient with Normal CSF Parameters and Radiographic Examinations. 29th Annual Meeting of The Infectious Diseases Association of Thailand. Hua-Hin, Prachuabkirikhan, Thailand October 4-7, 2003.

* = principal investigator 

10.  Suandork P, Kulwichit W*, Arunyingmongkol K, Krajiw S, Prommalikit O, Pancharoen C, Nisalak A, Thisyakorn U. Diagnosis of Dengue Virus Infection by Detection of Specific Immunoglobulin in Oral Fluid. 11th International Congress on Infectious Diseases. Cancun, Mexico. March 4-7, 2004.

* = principal investigator

11.  Prommalikit O, Kulwichit W*, Arunyingmongkol K, Krajiw S, Suandork P, Pupaibool J, Jaimchariyatam N, Pancharoen C, Nisalak A, Thisyakorn U. Detection of Urinary Antibody as a Tool for Diagnosis of Dengue Infection. 11th International Congress on Infectious Diseases. Cancun, Mexico. March 4-7, 2004.

* = principal investigator 

       12. Hansasuta P, Incomserb P, Buranapraditkun S, Kulwichit W, Rickinson AB,

Bhattarakosol P. Lack of EBV-specific immunes responses in severely immunocompromised patients. 15th International AIDS Conference. Bangkok, Thailand. July 11-16, 2004. 

13. Riengchan P, Suankratay C, Kulwichit W, Hanvanich M. Disseminated melioidosis in an HIV-infected patient. 15th International AIDS Conference. Bangkok, Thailand. July 11-16, 2004.14. Srisawat N, Nilgate S, Krajiw S, Unhasuta C, Chongthaleong A, Kulwichit W.* Inaccuracies on Leuconostoc Identification by Analytical Profile Index (API) Systems. 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. USA. October 30- November 2, 2004.       * = principal investigator

 15. Pupaibool J, Jaimchariyatam N, Suandork P, Prommalikit O, Sittichai R, Krajiw S, Arunyingmongkol K, Pancharoen C, Thisyakorn U, Kulwichit W.* Diagnosis of dengue infection by enzyme-linked immunosorbent assay and reverse transcription-nested polymerase chain reaction from dried urine spots on filter paper. 15th European Congress of Clinical Microbiology and Infectious Diseases. Copenhagen, Denmark. April 2-5, 2005.

 * = principal investigator   

16.  Jaimchariyatam N, Pupaibool J, Krajiw S, Arungyingmongkol K, Suandork P, Prommalikit O, Sittichai R, Nisalak A, Pancharoen C, Thisyakorn U, Kulwichit W.* Diagnosis of dengue infection by reverse transcription-nested polymerase chain reaction and enzyme linked immunosorbent assay using whole blood stored on filter paper.  15th European Congress of Clinical Microbiology and Infectious Diseases. Copenhagen, Denmark. April 2-5, 2005. (oral presentation = 7% of approx. 2,400 submitted abstracts)

This work received ESCMID (European Society of Clinical Microbiology and Infectious Diseases) Award for selected high-quality abstracts.

       * = principal investigator 

17. Kulwichit W, Nilgate S, Krajiw S, Srisawat N, Unhasuta C, Chongthaleong A. Enigmatic Leuconostoc and Lactobacillus Infections. 15th European Congress of Clinical Microbiology and Infectious Diseases. Copenhagen, Denmark. April 2-5, 2005. 

18. Kulwichit W, Chatsuwan T, Unhasuta C, Pulsrikarn C, Bangtrakulnonth A, Chongthaleong A. Nontyphoidal Salmonella invasive bloodstream infections resistant to quinolone and/or an extended spectrum cephalosporin in a country with extensive use of these antimicrobials in food animals. 16th European Congress of Clinical Microbiology and Infectious Diseases. Nice, France. April 1-4, 2006. 

19. Jaimchariyatam N, Kawkitinarong K*, Naweewitphadung K, Udomsantisuk N, Tumwasorn S, Kulwichit W*. Diagnosis of tuberculous pleuritis by nested polymerase chain reaction: a comparison of four different volumes of pleural fluid. 16th European Congress of Clinical Microbiology and Infectious Diseases. Nice, France. April 1-4, 2006.

       * = KK & WK share principal investigatorship 

20. Pupaibool J, Krajiw S, Arunyingmongkol K, Nisalak A, Pancharoen C, Thisyakorn U, Kulwichit W.* Diagnosis of dengue infection by enzyme-linked immunosorbent assay and reverse transcription-polymerase chain reaction from oral specimens. 16th European Congress of Clinical Microbiology and Infectious Diseases. Nice, France. April 1-4, 2006.

       * = principal investigator

This work received ESCMID (European Society of Clinical Microbiology and Infectious Diseases) Award for selected high-quality abstracts. 

21. Kulwichit W, De BK, Putcharoen O, Nilgate S, Hiransuthikul N. Brucellosis in Thailand: emerging and enigmatic. 17th European Congress of Clinical Microbiology and Infectious Diseases. Munich, Germany. March 31-April 3, 2007.

22. Yingsiwaphat V, Siriyasatien P, Arunyingmongkol K, Krajiw S, Pupaibool J, Nisalak A, Pancharoen C, Thisyakorn U, Kulwichit W.* Survival of dengue virus in the urine of acutely-infected patients – implications for pathogenesis and for a possible unrecognised mode of transmission for an arthropod-borne virus. 17th European Congress of Clinical Microbiology and Infectious Diseases. Munich, Germany. March 31-April 3, 2007.

      (Oral Presentation = 8.2% of 2,920 submitted abstracts)]

       * = principal investigator

      ESCMID (European Society of Clinical Microbiology and Infectious Diseases) Travel Grant Award for qualified abstracts 

23. Putcharoen O, Krajiw S, Nilratanakul V, Rojnuckarin P, Bhattarakosol P, Nisalak A,  Pancharoen C, Thisyakorn U, Kulwichit W.* Presence of dengue virus genome in the bone marrow of asymptomatic adults in a dengue-hyperendemic country: implication for complicated dengue pathogenesis. 17th European Congress of Clinical Microbiology and Infectious Diseases. Munich, Germany. March 31-April 3, 2007.

      (Oral Presentation = 8.2% of 2,920 submitted abstracts)

       * = principal investigator

      ESCMID (European Society of Clinical Microbiology and Infectious Diseases) Travel Grant Award for qualified abstracts 

24. Suwanpimolkul G, Pongkumpai M, Kulwichit W, Suankratay C. A randomised trial of 2% chlorhexidine in 70% alcohol compared with 10% povidone-iodine for venipuncture site disinfection: effects on blood culture contamination rates. 17th European Congress of Clinical Microbiology and Infectious Diseases. Munich, Germany. March 31-April 3, 2007.

      (Oral Presentation = 8.2% of 2,920 submitted abstracts) 

25. Putcharoen O, Kulwichit W, Tantawichien T, Hanvanich M, Suankratay C. A comparative study of treatment outcome in cryptococcal meningitis in HIV-infected patients during period before versus after implementation of treatment guidelines for management of increased intracranial pressure. 17th European Congress of Clinical Microbiology and Infectious Diseases. Munich, Germany. March 31-April 3, 2007.

(Oral Presentation = 8.2% of 2,920 submitted abstracts) 

26. Putcharoen O, Suwanpimolkul G, Pongkumpai M, Nilgate S, Kulwichit W, Tantawichien T, Hanvanich M, Suankratay C. Significance of  Streptococcus bovis biotype II/2  bacteraemia in patients with chronic liver diseases. 17th European Congress of Clinical Microbiology and Infectious Diseases. Munich, Germany. March 31-April 3, 2007.        

 

 

Publications & Correspondence:

 

  1. Chayakul P, Ovartlarnporn B, Kulwichit W, Piratvisut T, Kunasakdakun A. Intestinal Capillariasis: Report of 2 cases from the Southern Thailand. J Infect Dis Antimicrob Agents 1988; 5: 187-90.

 

2.   Chayakul P, Silpapojakul K, Krisanapan S, Kulwichit W. Leptospirosis: Clinical Manifestations in a Recent Outbreak. J Infect Dis Antimicrob Agents 1989; 6: 194-201.

 

3.    Ovartlarnporn B, Kulwichit W, Hiranniramol S. Medication-Induced Esophageal Injury: Report of 17 cases with Endoscopic Documentation. Am J Gastroenterol 1991; 86(6): 748-50.

Impact factor 2006 = 5.61

 

4.   Ovartlarnporn B, Kulwichit W. Tetracycline-Induced Esophageal Ulcer: A Condition That Is Probably More Common Than It Appears To Be. J Med Assoc Thai 1991; 74: 443-7.

Citations to June 2007 = 7

 

5.     Kulwichit W, Wehbie RS. The Impact of Human Immunodeficiency Virus on Syphilis. Res Staff Phys 1994; 40(suppl 1):24-6. 

6.   Kulwichit W. Antiviral Chemoprophylaxis After Occupational Exposure to Human Immunodeficiency Virus. Am J Ophthalmol 1998; 126(2): 328.

Impact factor 2006 = 2.47

 

7.   Kulwichit W, Edwards RH, Davenport EM, Baskar JF, Godfrey V, Raab-Traub N. Expression of the Epstein-Barr Virus Latent Membrane Protein 1 Induces B Cell Lymphoma in Transgenic Mice. Proc Natl Acad Sci USA 1998; 95(20): 11963-8.

Impact factor 2006 = 9.64

 

8.   Uchida J, Yasui T, Takaoka-Shichijo Y, Muraoka M, Kulwichit W, Raab-Traub N, Kikutani H. Mimicry of CD40 Signals by Epstein-Barr Virus LMP1 in B Lymphocyte Responses. Science 1999; 286(5438): 300-3.

Impact factor 2006 = 30.03

 

9.   Kulwichit W. Malaria in a Trinidadian Man. N Engl J Med 2000; 343(14): 1046-7.

Impact factor 2006 = 51.3

 

10. Amador-Zarco JJ, Mora-Tiscareno A, Sangri-Pinto AG, Braun-Roth G, Dressler LG, Kulwichit W, Van Dyke T, Calderon-Garciduenas L. Nasal squamous cell carcinoma in a child J Otolaryngol 2002; 31(1): 45-9.

Impact factor 2006 = 0.37 

11. Pancharoen C, Kulwichit W, Tantawichien T, Thisyakorn U, Thisyakorn C. Dengue infection: a global concern. J Med Assoc Thai 2002; 85 suppl 1: S25-33.Citations to June 2007 = 10

 

12. Tanyaowalak W, Sunthornyothin S, Luengtaviboon K, Suankratay C, Kulwichit W.* Mycotic Aneurysm Caused by Burkholderia pseudomallei with Negative Blood Cultures. Scand J Infect Dis 2004; 36(1): 68-70. * = corresponding author

Impact factor 2006 = 1.56

13. Kulwichit W, Torranin P. Glucose-6-Phosphate Dehydrogenase Deficiency, Vitamin K, and Ambiguity in Medical Textbooks. Acta Haematol 2004; 111(3): 173-4.

Impact factor 2006 = 1.56 

14. Kulwichit W. First-line and second-line antiretroviral therapy. Lancet 2004; 364(9431): 329-30.

Impact factor 2006 = 25.8 

15. Kulvichit K, Kulwichit W, Lumbiganon P. Clinical Trial Registration. N Engl J Med 2005; 352(2): 198-9.

Impact factor 2006 = 51.3 

16. Bronnert J, Malhotra C, Suavansri K, Hanvesakul R, Kulwichit W, Wilde H. Complete Ptosis Caused by Dengue Fever. Lancet 2005; 366(9501): 1982.

Impact factor 2006 = 25.8 

17.  Thornburg NJ*, Kulwichit W*, Edwards RH*, Shair KHY, Bendt KM, Raab-Traub N. LMP1 Signaling and Activation of NF-κB in LMP1 Transgenic Mice. Oncogene 2006; 25(2): 288-97.

* = These authors contributed equally to this work.

Impact factor 2006 = 6.6 

 18. Pupaibool J, Chindamporn A, Patarakul K, Suankratay C, Sindhuphak W, Kulwichit   W.* Human Pythiosis. Emerg Infect Dis 2006; 12(3): 517-8.

        * = corresponding author

          Impact factor 2006 = 5.09 

19. Incomserb P, Bhattarakosol P, Kulwichit W, Chantratita W, Hansasuta. Establishment of real-time polymerase chain reaction-based assay for quantitation of Epstein-Barr virus DNA in healthy donors and in patients with EBV associated lymphomas. J Med Assoc Thai 2005; 88 suppl 4: S280-6.

       

20. Krajaejun T, Sathapatayavongs B, Pracharktam R, Nitiyanant P, Leelachaikul P, Wanachiwanawin W, Chaiprasert A, Assanasen P, Saipetch M, Mootsikapun P, Chetchotisakd P, Lekhakula A, Mitarnun W, Kalnauwakul S, Supparatpinyo K, Chaiwarith R, Chiewchanvit S, Tananuvat N, Srisiri S, Suankratay C, Kulwichit W, Wongsaisuwan M, Somkaew S. Clinical and epidemiological analyses of human pythiosis in Thailand. Clin Infect Dis 2006;43(5):569-76.

       Impact factor 2006 = 6.19 

21. Kulwichit W, Chatsuwan T, Unhasuta C, Pulsrikarn C, Bangtrakulnonth A, Chongthaleong A. Drug-resistant nontyphoidal Salmonella bacteremia, Thailand. Emerg Infect Dis 2007;13(3):501-2.

       Impact factor 2006 = 5.09 

22.  Kulwichit W, Nilgate S, Chatsuwan T, Krajiw S, Unhasuta C, Chongthaleong A. Accuracies of Leuconostoc Phenotypic Identification: A Comparison of API Systems and Conventional Phenotypic Assays. BMC Infect Dis 2007;7:69.

        Impact factor 2006 = 1.90 

23.  Kittisupamongkol W, Kulwichit W.* Relapsing polychondritis or ANCA-negative Wegener's granulomatosis?" Med J Aust 2007;187(8):478-9.
       * = corresponding author
         Impact factor 2006 = 2.58

 

Invited Talks: International Conferences and Seminars

 

  1. “Updates on Dengue Diagnosis and Pathogenesis” at The 2nd Asian Congress of Pediatric Infectious Diseases, Kota Kinabalu, Sabah, Malaysia. September 2-4, 2004.

 

  1. “Dengue Infection” Special Seminar - The University of North Carolina School of Medicine, Chapel Hill, NC, USA. October 29, 2004.

 Book Chapters (International only) 

1. Poligone B, Kulwichit W. Sexually Transmitted Diseases. In: Manual of Dermatologic Therapeutics : with essentials of diagnosis. pp 185-98. Kenneth A. Arndt and Jeffrey T.S. Hsu. Editors. 2007; 7th Edition. Lippincott Williams & Wilkins.

 

2. Gilmore ES, Kulwichit W. Immunocompromised Patients: Human Immunodeficiency

Virus- and Non-Human Immunodeficiency Virus Positive. In: Manual of Dermatologic Therapeutics : with essentials of diagnosis. pp 118-27. Kenneth A. Arndt and Jeffrey T.S. Hsu. Editors. 2007; 7th Edition. Lippincott Williams & Wilkins.